Health

The alterations in the handling of calcium by the body are responsible for a large percentage of kidney stones. The changes in calcium metabolism are frequently accompanied by abnormalities in the metabolism of two compounds that are products of the chemical reactions that constantly keep us going: oxalate and uric acid. Attempts at curbing the incidences of kidney stones include control of the metabolism of calcium, oxalate, and uric acid. While all these compounds are part of the normal composition of our bodies.

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particularly problematic type of stone is that associated with infection. These are formed when infections with urea-splitting organisms are present. These bugs take urea and transform it into ammonia, which forms a complex with magnesium and phosphate to become something called struvite which is the most important component of “infectious” stones. It is not easy to cure these, and they grow to form large “staghorn” calculi (stones) that get trapped in the pelvis of the kidney and cause a lot of problems.


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